Determinants of Industrial Property Rents in the Chicago Metropolitan Area

Urban economists have long understood the theoretical importance of transportation infrastructure and accessibility on the location choice of households and firms. We utilize a readily available data set of transaction rents in the Chicago metropolitan area to investigate the determinants of industrial property rents. Among the factors considered are proximity to transportation infrastructure, characteristics of the property, the term structure of lease agreements, and local attributes of the neighborhood. Empirical results suggest property, lease, and local demographics play important roles in determining rents. Despite the fact that industrial property tends to locate very close to rail lines and interstate highways, transportation infrastructure has much less influence. There is evidence that there is an upward sloping lease term structure premium and that the premium varies over time. The model is also used to develop a constant quality rent index for the Chicago commercial property market. Compared to average rents and asking rents, the estimated constant quality index shows a smaller run up in rents from 2003 through 2008 and a larger drop off in rents through the end of 2011

Current issues in the characterisation of toxicological impacts

Fate, exposure and effect measures provide a basis for the calculation of characterisation factors in Life Cycle Assessment (LCA). Such characterisation factors provide insights into the relative concern of chemical emissions within and across life cycle inventories, in the context of toxicological stress to humans and to ecosystems. A brief overview is presented in this paper of the available options for toxicological characterisation and of associated issues that will need to be addressed in future consensus-building initiatives. An introduction is provided to issues such as: (1) the benefit of measures calculated at midpoints versus at endpoints in the toxicological cause-effect chains (sometimes termed environmental mechanisms); (2) the need to use multimedia models with spatial resolution; (3) the political consequences of accounting for variations in population density; (4) uncertainties in the toxicological potency measures; and (5) the different options for the toxicological endpoint measure(s). These issues are addressed under the headings of Fate and Exposure, Human Health and (aquatic) Ecosystem Healt

Faith-Based Organizational Values and International Business Transactions

The general business problem is conflicting values between faith-based businesses and hosting countries can adversely affect business performance. The problem may be the gap between business leaders and organizational values and host country values. The specific business problem is some faith-based business leaders lack strategies to mitigate incongruousness between the core values of their organizations and the contrary values of foreign cultures to effectively conduct international business. The purpose of this qualitative case study research is to explore what strategies biblically based business leaders use to mitigate incongruousness between the core values of their business and contrary values of foreign cultures in international business transactions to maximize organizational performance. The theoretical framework of this study is the theory of planned behavior and value-based leadership. The two are complementary and can be used to positively impact business transactions by mitigating the incongruences between values and profit maximization. The significance of this study is that the data supports the ideas that leaders can influence behavioral outcomes through strategies that focus on biblical based values and policies. Additionally, these strategies align with biblical teachings

Towards an overall framework to assess the sustainability of the use of natural resources

Over the years, the sustainable supply of natural resources for the global economy has drawn increasing political interest. The efficient use of resources is a fundamental issue for sustainability assessment, entailing and affecting environmental, economic and social aspects. It is not surprising that they hold a central role in many different sustainability assessment frameworks. In conventional life cycle assessment (LCA), natural resources are considered as one area of protection (AoP). It is well recognized that the typical approach of this AoP starts from the provisioning function of resources, but natural resources however are also dealt with in totally different frameworks. If one starts from an ecological point of view, provisioning services is only one role natural resources fulfill next to regulating, cultural and supporting functions, all captured by the Ecosystems Services framework. The access to certain resources is a further issue of concern for policy. The identification of the so-called Critical Raw Materials for EU took into account their economic importance for specific sectors and supply risk, the latter being focused on concentration of supply from producing countries showing poor governance and low environmental standards, in turn mitigated by substitutability and recyclability of the materials. Further on, there is no doubt that resource exploitation and use may affect several social aspects (e.g. working conditions) as can be identified by the Social Hotspot Database, and that emissions generated along their use in supply chains (from extraction to manufacturing, use and end of life) might affect human health and natural ecosystems, other two areas of protection in conventional LCA. This presentation proposes an integration of the aforementioned frameworks aiming at depicting an overall framework to assess the sustainability of the use of natural resources

Brain GABA and Glutamate Concentrations Following Chronic Gabapentin Administration: A Convenience Sample Studied During Early Abstinence From Alcohol.

Gabapentin (GBP), a GABA analog that may also affect glutamate (Glu) production, can normalize GABA and Glu tone during early abstinence from alcohol, effectively treating withdrawal symptoms and facilitating recovery. Using in vivo magnetic resonance spectroscopy, we tested the degree to which daily GBP alters regional brain GABA and Glu levels in short-term abstinent alcohol-dependent individuals. Regional metabolite levels were compared between 13 recently abstinent alcohol-dependent individuals who had received daily GBP for at least 1 week (GBP+) and 25 matched alcohol-dependent individuals who had not received GBP (GBP-). Magnetic resonance spectra from up to five different brain regions were analyzed to yield absolute GABA and Glu concentrations. GABA and Glu concentrations in the parieto-occipital cortex were not different between GBP- and GBP+. Glu levels in anterior cingulate cortex, dorsolateral prefrontal cortex, and basal ganglia did not differ between GBP- and GBP+. However, in a subgroup of individuals matched on age, sex, and abstinence duration, GBP+ had markedly lower Glu in the frontal white matter (WM) than GBP-, comparable to concentrations found in light/non-drinking controls. Furthermore, lower frontal WM Glu in GBP+ correlated with a higher daily GBP dose. Daily GBP treatment at an average of 1,600 mg/day for at least 1 week was not associated with altered cortical GABA and Glu concentrations during short-term abstinence from alcohol, but with lower Glu in frontal WM. GBP for the treatment of alcohol dependence may work through reducing Glu in WM rather than increasing cortical GABA

Toward an overall analytical framework for the integrated sustainability assessment of the production and supply of raw materials and primary energy carriers

The sustainable production and supply of raw materials (nonenergy raw materials) and primary energy carriers (energy raw materials) is a core element of many policies. The natural resource base for their production and supply, and the access thereto, are limited. Moreover, raw material supply is high on environmental and social impact agendas as well. A broad, quantitative framework that supports decision makers is recommended so as to make use of raw materials and primary energy carriers more sustainably. First, this article proposes a holistic classification of raw materials and primary energy carriers. This is an essential prerequisite for developing an integrated sustainability assessment framework (ISAF). Indeed, frequently, only a subset of raw materials and primary energy carriers are considered in terms of their source, sector, or final application. Here, 85 raw materials and 30 primary energy carriers overall are identified and grouped into seven and five subgroups, respectively. Next, this article proposes a quantitative ISAF for the production and supply of raw materials and primary energy carriers, covering all the sustainability pillars. With the goal of comprehensiveness, the proposed ISAF integrates sustainability issues that have been covered and modeled in quite different quantitative frameworks: ecosystem services; classical life cycle assessment (LCA); social LCA; resource criticality assessment; and particular international concerns (e.g., conflict minerals assessment). The resulting four areas of concerns (i.e., environmental, technical, economic, and social/societal) are grouped into ten specific sustainability concerns. Finally, these concerns are quantified through 15 indicators, enabling the quantitative sustainability assessment of the production and supply of raw materials and primary energy carriers

Switch and template pattern formation in a discrete reaction diffusion system inspired by the Drosophila eye

We examine a spatially discrete reaction diffusion model based on the interactions that create a periodic pattern in the Drosophila eye imaginal disc. This model is capable of generating a regular hexagonal pattern of gene expression behind a moving front, as observed in the fly system. In order to better understand the novel switch and template mechanism behind this pattern formation, we present here a detailed study of the model's behavior in one dimension, using a combination of analytic methods and numerical searches of parameter space. We find that patterns are created robustly provided that there is an appropriate separation of timescales and that self-activation is sufficiently strong, and we derive expressions in this limit for the front speed and the pattern wavelength. Moving fronts in pattern-forming systems near an initial linear instability generically select a unique pattern, but our model operates in a strongly nonlinear regime where the final pattern depends on the initial conditions as well as on parameter values. Our work highlights the important role that cellularization and cell-autonomous feedback can play in biological pattern formation

Research Needs and Challenges from Science to Decision Support. Lesson Learnt from the Development of the International Reference Life Cycle Data System (ILCD) Recommendations for Life Cycle Impact Assessment

Environmental implications of the whole supply-chain of products, both goods and services, their use, and waste management, i.e. their entire life cycle from "cradle to grave" have to be considered to achieve more sustainable production and consumption patterns. Progress toward environmental sustainability requires enhancing the methodologies for environmental integrated assessment and promoting their use in different domains. In the context of Life Cycle Assessment of products, in the last years, several methodologies have been developed for Life Cycle Impact Assessment (LCIA) and some efforts have been made towards their harmonisation. In this context, the Joint research centre (JRC) of the European Commission led a “science to decision support” process which resulted in the International Reference Life Cycle Data System (ILCD) Handbook. The Handbook provides guidelines to methods and assessments to assess emissions into air, water and soil, as well as the natural resources consumed in terms of their contributions to different impacts on human health, natural environment, and availability of resources. Those guidelines come from a comprehensive process of selection of methods based on a set of scientific and stakeholder acceptance criteria and involving experts, advisory groups and the public. In this “from science to decision support” process a number of research needs, critical issues and challenges for LCIA emerged and are presented here as a basis for development, both in terms of comprehensiveness of the impact coverage and of the further mainstreaming of sustainability concept.JRC.H.8-Sustainability Assessmen